Monkeypox Virus/Orthopoxvirus

CPT code: 87593
ORDERING rECOMMENDATION

Use to detect the orthopoxviruses, including the Monkeypox virus

specimen required

Specimen Type:

Lesion swab; swab the lesion vigorously to collect an appropriate amount of DNA. Lesions do not have to be deroofed prior to swabbing.

Collection Tube:

Universal Transport System (Tube with Media); Request Supplies

Minimum Volume:

3.0mL viral transport media

Specimen Stability/Storage:

Refrigerated (2-8°C): ≤ 7 days or Frozen (≤ -20°C): 30 days

Unacceptable Conditions:

Room Temperature (15-25°C): place specimen in refrigerator or freezer within 5 minutes of collection.

Shipping Requirements:

Call 866-983-0667 to schedule courier pickup

Stability:

Refrigerated: 7 days; Frozen: 30 days

devlab test code
metholodogy

V10005

Nucleic Acid Amplification

performed
reported

Daily (Monday – Friday)

Within 24 hours from receipt (Monday – Friday)

ALTERNATIVE NAMES

Monkeypox, Poxvirus, Monkeypox Virus

SUBMIT WITH ORDER

Signed Test Requisition and Public Health Demographics Form

Results Interpretation

Positive:

Result is consistent with Monkeypox virus infection

Inconclusive:

Results are inconclusive; please consider submitting a new specimen

Negative:

Monkeypox viral DNA not detected

NOTE: This test does not differentiate members of the orthopoxvirus genus. Vesicular specimens obtained from those infected with non-variola orthopoxvirus, e.g., vaccinia, monkeypox virus, cowpox, should produce a positive result in this assay. In the United States, a positive result is most likely due to infection with monkeypox virus or vaccinia virus. Other orthopoxviruses may be considered if appropriate. Refer to the US Centers for Disease Control and Prevention if additional confirmatory testing is needed.